Roll Call of Credible Experts Advocating Vitamin D for COVID-19
Jan, 2021 (w/ Feb updates) One-Page Executive Summary Karl Pfleger1 PhD
Recommending vitamin D for COVID-19 is supported by multiple large groups of scientific, medical, & public health experts, many top global vitamin D researchers, plus notable public health officials. This is a summary:
Jan’21 French review in La Revue du Praticien: 73 French authors with the support of 6 national scientific societies.
Prophylaxis: 20-60ng/ml; 1200 IU/day. 2x for obesity. 4000 IU safe. Treatment: 100,000 IU on diagnosis, repeated 7 days later.
Dec’20 international VitaminDforAll open letter: 220 signatories from 33 countries, almost all medical doctors & PhDs, including over 100 professors, many notable top vitamin D experts.
Prophylaxis: min 30ng/ml; 10,000 IU/day for 2-3 weeks then 2000-4000 IU/day. More (eg 2x) if overweight/etc.Treatment: Test & treat deficiency, eg w/ [Castillo’20] or [Rastogi’20] protocols.
Dec’20 Italian Academy of Medicine of Turin letter: 152 Italian professors & physicians.
Prophylaxis: min 40ng/ml; up to 4000 IU/day. Treatment: Protocol of [Annweiler’20], [Castillo’20], or [Rastogi’20].
Apr’20 Grant et al Nutrients paper: cited by 805 other scholarly works w/ thousands of authors in total, per Google Scholar.
Prophylaxis: 40-60ng/ml; 10,000 IU/day for 2-3 weeks then 5000 IU/day. Treatment: “higher vitamin D3 doses might be useful.”
Dec’20 Griffin et al Royal Society evidence synthesis: 8 mostly UK authors.
Prophylaxis: 20+ng/ml; 4000 IU/day for 4 weeks in likely deficient, 800-1000 IU/day. 4000 IU safe. Treatment: test or supplement.
PPX: 1000-3000 IU/day. Tx: Outpatient 4000 IU/day. Hospital: calcifediol (see link) or 20,000-60,000 IU then 20,000 IU/week.
Nov’20 Irish Covit-D Consortium position statement: 9 Irish medical experts from “across Ireland’s leading universities”.
PPX: 20+ng/ml +widespread testing for deficiency & achievement; 800-1000 IU/day. More if overweight/etc. 4000 IU/day safe.
Eradicate deficiency w/ aggressive supplementation. 4000 IU safe.
Vitamin D does impact infection risk and he takes it.
Might help. 800-2000 IU/day prob. safe. 1000 IU/day reasonable.
Rows 1-4, 5-7, & 8-10 represent groups on the order of 100, 10, & 1 experts respectively. An expanded table includes more entries: Eg French Natl Acad Med, Spanish gerontological soc, & Walter Willett, 2nd most cited author in medicine.
Consensus of the recommendations of the above groups and individuals:
1. There is clear consensus that evidence is now sufficient to recommend action without waiting for more data.
2. There is clear consensus that vitamin D deficiency is important for COVID-19 and should be urgently fixed.
3. Most recommend vitamin D for both prevention and treatment of COVID-19.
4. There is almost unanimous agreement to achieve at least 20ng/ml (50nmol/L) serum levels.
5. There is clear consensus to recommend daily intakes above current government guidelines, though amounts span a wide range from 800-5000 IU/day. Almost everyone emphasizes the safety of 4000 IU/day.
Some other experts disagree and call for more research, though no disagreeing groups of sizes similar to the top rows above are apparent. Officials in most jurisdictions have not yet added vitamin D as a top level pandemic mitigation measure alongside distancing, masks, and vaccines. Vitamin D’s importance for COVID-19 has sometimes been labeled misinformation, but clearly it is not as the aggregate expertise here shows. This is an active area of scientific & public health research and discussion. We will someday be better able to estimate which vitamin D policies would have saved the most lives. Meanwhile, the arrayed expertise here suggests that lives could be saved by increased official vitamin D recommendations. Those opposed say only that this is not sufficiently proven, not that increasing vitamin D recommendations is likely to cost more lives than it would save. The imbalance of risk is clear. Many lives are still on the line.
1 Independent Philanthropist, Investor, & Researcher. Longevity industry analyst, AgingBiotech.info (non-profit). Philanthropic organizer, VitaminDforAll.org (non-profit). No conflicts of interest related to vitamin D. HTML version